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IGF – Serum insulin-like growth factor-1 and C-reactive protein concentrations before
Theriogenology. 2014 Dec 1;
Authors: Dabrowski R, Szczubial M, Kostro K, Wawron W, Ceron JJ, Tvarijonaviciute A
Abstract
Pyometra is one of the most common diseases of the reproductive system in bitches. The inflammatory processes occurring in the uterus result in changes in concentrations of numerous serum biomarkers, which are used for monitoring the postoperative period. The aim of the present report was to study the evolution of serum levels of insulin-like growth factor-1 (IGF-1) and C-reactive protein (CRP) in bitches suffered from pyometra and after ovariohysterectomy in comparison with the control group of healthy dogs submitted to the surgery. Our results indicate that the serum level of IGF-1 is decreased (101.6.ng/mL [73.8-177.8.ng/mL]), whereas CRP is increased (114.6.?g/mL [95.3-131.6.?g/mL]) during severe inflammation. When inflammation caused by pyometra and surgery is resolved, the level of IGF-1 is increased (186.0.ng/mL [94.6-344.3.ng/mL], P.
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IGF - Serum insulin-like growth factor-1 and C-reactive protein concentrations before
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