New Exercise and Fitness Review
Zhongguo Dang Dai Er Ke Za Zhi. 2014 Dec;16(12):1236-1240
Authors: Zheng F, Wang X, Wang X
Abstract
OBJECTIVE: To study the effects of recombinant human growth hormone (r-hGH) replacement therapy on glucose and lipid metabolism and thyroid function in children with idiopathic short stature (ISS).
METHODS: Forty-seven ISS children with a mean age of 10±3 years treated between January 2009 and January 2013 were enrolled. All children underwent r-hGH replacement therapy for 3-24 months and were followed up once every 3 months. Fasting blood glucose (FBG), insulin (INS), blood lipids and thyroid function were measured before treatment and after 0-1 and 1-2 years of treatment.
RESULTS: After treatment with r-hGH, there were no significant changes in FBG, INS, insulin sensitivity index (ISI), and FBG/INS ratio (FGIR), but the FGIR showed a declining trend. The percentage of patients with FGIR
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Human Growth Hormone - [Effects of r-hGH replacement therapy on glucose and lipid met
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