New Exercise and Fitness Review
Background: Creatine monohydrate has become a very popular nutritional supplement for its ergogenic effects. The safety of creatine monohydrate has previously been confirmed. However with each novel form of creatine that emerges, its safety must be verified. Therefore, the purpose of this study was to examine the safety of a novel form of creatine, creatine nitrate (CN), over a 28.day period. Methods: 58 young males and females (Pooled: 24.3?±?3.9.years, 144.9?±?8.0.cm, 74.2?±?13.0.kg) participated in this study across two laboratories. Subjects were equally and randomly assigned to consume either 1.g (n?=?18) or 2.g (n?=?20) of CN or remained unsupplemented (n?=?20). Blood draws for full safety panels were conducted by a trained phlebotomist prior to and at the conclusion of the supplementation period. Results: Pooled data from both laboratories revealed significant group x time interactions for absolute lymphocytes and absolute monocytes (p?
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28 days of creatine nitrate supplementation is apparently safe in healthy individuals
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